CKD or Chronic Kidney Diseases affect approximately 195 million women worldwide.
At present it also ranks 8th in the leading causes of death in women, causing around 600,000 deaths each year.
Pregnancy is a unique challenge and is a major cause of acute kidney injury (AKI) in women of childbearing age; AKI and pre-eclampsia (PE) may lead to subsequent CKD, but the entity of the risk is not completely known. CKD has a negative effect on pregnancy even at very early Stages. Specific systemic conditions like Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA), and Systemic Scleroderma (SS), are more likely to affect women than men.
Women with CKD have a higher cardiovascular risk Blood pressure is a major determinant of atherosclerosis and developing ESRD; therefore, the gender difference in systolic blood
pressure may contribute to the slower decline in GFR in women. Other plausible explanations for the gender differences in GFR decline include hormonal status and lifestyle differences, such as dietary protein intake, salt, smoking, and alcohol intake.
Renal disease in women with polycystic kidney disease, eg: A nephropathy, membranous
glomerulopathy, and ‘chronic renal disease of unknown aetiology’ progresses at a slower rate than it does in blood pressure- and lipid levels-matched men with these diseases. Loss of renal function was slower in women than in men, especially in women who were younger and
predominantly premenopausal.
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